Fig. 7. Acid-activated total Na⁺/H⁺ exchange rates in differentiated C2PLKO.1 andC2NHE2KD cells. Both apical and basal sides of the cell monolayer were perfused with Na⁺-containing solution without inhibitors. (A) pH_i recovery curve in C2PLKO.1 cells, (B) in C2NHE2KD cells. (C) Comparison of acid-activated Na⁺/H⁺ exchange rates in C2PLKO.1 and C2NHE2KD cells. (D) Comparison of initial pH_i at the beginning of acid-induced pH_i recovery. (n=5, mean ± SEM).